One thing that is different is how the CG shifts as fuel burns. The front engine planes as they burn fuel actually get easier to fly as the CG moves rearward. Easier to trim, actually can gain speed as the trim drag lessens. Your plane starts to loose it’s agility as you burn fuel. Your plane at landing feels like everyone else’s taking off. You gain trim drag, the less fuel you have. This is the price of your configuration. What you are doing is lessening the impact as much as possible with your tail change. Aft CG can be dangerous if too far aft, but aft CG in a good spot makes a nice flying airplane. Forward CG is safer to fly in that it is more stable; it is stable because it is in the “ heavy “ damping range of the CG.